Open AccessMisexpression ofBREgene in the developing chick neural tube affects neurulation and somitogenesis
Author(s) -
Guang Wang,
Yán Li,
Xiaoyu Wang,
Manli Chuai,
John Yeuk-Hon Chan,
Jiang Lei,
Andrea Münsterberg,
Kenneth K. Lee,
Xuesong Yang
Publication year - 2015
Publication title -
molecular biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.463
H-Index - 225
eISSN - 1939-4586
pISSN - 1059-1524
DOI - 10.1091/mbc.e14-06-1144
Subject(s) - somitogenesis , biology , neural tube , neurulation , neural crest , neural fold , neural plate , microbiology and biotechnology , embryo , neurogenesis , embryogenesis , somite , neuroepithelial cell , embryonic stem cell , anatomy , gene , genetics , gastrulation
This is the first study of the role of BRE in embryonic development using early chick embryos. BRE is expressed in the developing neural tube, neural crest cells, and somites. BRE thus plays an important role in regulating neurogenesis and indirectly somitogenesis during early chick embryo development.