Open AccessManganese ferrite nanocubes as an MRI contrast agent
Author(s) -
Ravichandran Manisekaran,
S. Velumani
Publication year - 2019
Publication title -
materials research express
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.383
H-Index - 35
ISSN - 2053-1591
DOI - 10.1088/2053-1591/ab66a4
Subject(s) - superparamagnetism , biocompatibility , materials science , spinel , remanence , ferrite (magnet) , manganese , nanotechnology , nuclear magnetic resonance , nanostructure , diffraction , magnetization , magnetic field , metallurgy , optics , composite material , physics , quantum mechanics
Facile synthesis of superparamagnetic, highly crystalline, manganese ferrite nanocubes (MnNCs) is reported. X-ray diffraction depicts single-phase face-centred cubic spinel and the electron microscopy represents the nearly monodispersed cube-like nanostructure with the size ranging from 18 to 20 nm. Vibrating sample magnetometer shows magnetization field-dependent curves at 300 K exhibiting the superparamagnetic behaviour of NCs with negligible remanence. Furthermore, the biocompatibility of NCs was proved by MTT assay. These unique characteristics make this NCs as a contrast agent ideally suited for T 2 -weighted MR imaging. This novel method of synthesizing NCs proves to be very attractive for various biomedical applications because of their outstanding stability and biocompatibility.
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