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Collagen is the result of determination from chitosan blood shells ( Anadara granosa ) and green shells ( Mytilus viridis) . Previous research, extraction was carried out to obtain collagen. The yield of collagen produced is 2.03% with a concentration of acetic acid 0.75 M. Collagen can penetrate the main components of the dermis skin layer (the bottom of the epidermis) made by fibroblast cells. Based on the results of previous studies, the collagen produced will be made into a dosage form so that it can be better utilized. Based on the description above, researchers are interested in comparing blood clam shells and green mussel shells with a study entitled the comparison of physical test blasting creams of Anadara granosa with green shells Mytilus viridis against the skin of male white rats. Laboratory experimental research using a post test control design research design in the form of post only design which is divided into 5 treatment groups with each group consisting of 5 male white rats. The negative control group by giving a base cream and the test group by giving blasting cream Anadara granosan with Mytilus viridis concentrations of 10%, 15%, 20% and 25%. The parameter observed was skin moisture level. The results of statistical analysis using the ANOVA test. The results of this study are blasting cream Anadara granosa and Mytilus viridis can provide a moisturizing effect on rat skin. The most optimal concentration as a moisturizing effect on rat skin is a concentration of 25%

Comparison of blasting cream anadara granosa with mytilus viridis in white rat skin(rattus novergicus)