English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

A synthesis of cellulose derivative membrane has been performed as good candidate for sustained release matrix. Alginate is a polysaccharide that water-soluble, consisting of β-D-manuronate and α-L-guluronate, and contains of carboxylic (–COOH) and hydroxyl (–OH) groups which allow to form hydrogen bonds with drug compounds. The purpose of this study is to determine the physicochemical properties of alginate membranes. The membranes were prepared by the solution casting method on polypropylene container. Structural characterization of the membrane was done by fourier transform infrared spectra (FTIR) and the mechanical properties of the membrane was analyzed with tensile strength test and elongation test based on variation of alginate concentration. Scanning Electron Microscopy (SEM) was done to determine the surface morphology of the membrane. The FTIR spectra showed the presence of carbonyl group (C=O) at 1597 cm −1  and hydroxyl group (–OH) at 3426 cm −1 . The tensile strength of membrane for alginate with different concentration at 3.3, 5, and 10% w/v were 8.84, 17.07, and 7.36 MPa, respectively. This indicates that the higher concentration of alginate membrane will increase the strength of the membrane, but at higher alginate concentration the membrane strength tend to decrease.

The preparation and characterization of cellulose derivative membrane as matrix for sustained release formulation