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With the aim to find endophytic actinomycetes that synthesize bioactive compounds over 800 strains were isolated from 53 desert plants of the Gobi-Sumber, Umnugobi, Dundgobi, Dornogobi, Bayankhongor, and Gobi-Altai provinces of Mongolia. The HPLC study of strains with high anti-quorum sensing and antibacterial activities revealed that they produced flavonoids and phenolic compounds. Molecular diversity evaluated with 16S rRNA gene sequences of 123 strains showed that they belonged to 12 genera:  Streptomyces, Promicromonospora, Micromonospora, Streptosporangium, Kribbella, Pseudonocardia, Nocardia, Micromonospora, Saccharothrix, Friedmanniella, Actinocatenispora,  and  Geodermatophilus,  the latter two genera were registered in Mongolia for the first time. Moreover, the genus  Actinocatenispora  was isolated from plants for the first time.

Bioactive compounds and molecular diversity of endophytic actinobacteria isolated from desert plants