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Nanotechnology is an applied science at the atomic scale. Nanotechnology engages the construction of small structures and devices by manipulating each of the molecules and atoms that has unique and strong characteristics. The aim of this research is to know the effect of long soaking of blood cockle ( Anadara  sp.) shells powder in the hydrochloric acid on the characteristics of nano calcium, which include particle size analysis, analysis of the levels of minerals, yield, and analysis of proximate (moisture and ash). The research using RAL with 4 treatments (control, soaking 24 hour, soaking 48 hour, soaking 72 hour) with 5 replicates. Particle size, levels of minerals, and analysis of proximate (moisture and ash) analyzed by descriptive methods, while the yield data were analyzed with statistic. The best result is on 48 hour treatment. It can be seen from the size of particles, the levels of minerals, and yield.

Effect of soaking time of blood cockle (Anadara sp.) shells powder with hydrochloric acid on the characteristics of nano calcium