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The article presents the results of molecular-genetic investigation of isolates of rabies virus was isolated from 2 rabies patients in Ukraine. It has been confirmed that the virus that caused the deaths belongs to animal lyssavirus, namely the rabies virus. It has been proved that street isolates from humans by their genetic characteristics belong to the first genotype (RABV), the first phylogroup of animal lyssavirus. High homology between experimental samples and materials from cats, dogs, and foxes from the territory of Ukraine and with isolates in fox populations in South-Eastern Europe was revealed. RT-PCR confirmed that 2 people died of rabies, the isolates belong to the first phylogroup of lissavirus, the first genotype (RABV). It is proved that 2 street isolates from people from Ukraine are similar in degree of homology to the isolates isolated in fox populations in South-Eastern Europe.

Molecular characteristics isolates of rabies virus isolated from humans in Ukraine