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We focus our attention on the influence of hydrophobic silver nanoparticles (Ag NPs) on the 1-Stearoyl-2-oleoylsn-glycero-3-phosphocholine (SOPC) model system. Results obtained by differential scanning calorimetry (DSC) and infrared (IR) spectroscopy were compared to their counterpart for lipid systems with incorporated hydrophobic gold nanoparticles (AuNPs) and pure SOPC lipid in a water environment. The results show a strong effect of hindering the gel-to-liquid crystalline phase transition for both types of noble metal hydrophobic NPs. The effect of the phase transitions shift to the lower temperatures is more pronounced for the silver particles for the concentrations studied. According to the IR spectral analyses, no negative effect is observed of the NPs on the lipid hydration for the concentration studied, and the plasmon effect of the Ag NPs appears to be more pronounced.

Silver nanoparticles synthesis and their effect on the SOPC lipid structure