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Gd 2 O 3 , SiO 2 -Gd 2 O 3  and SiO 2 -MnO 2  nanoparticles were produced by the method of pulsed electron evaporation of oxide targets with condensation of the vapors in a vacuum. These materials are considered as probable contrast agents for magnetic resonance imaging (MRI). The Gd 2 O 3  nanoparticles exhibit a rather high r1 and r2 relaxivities. These results point to the potential of using nanocrystals for MRI diagnosis. The mesoporous nanostructures SiO 2 -Gd 2 O 3  and SiO 2 -MnO 2  could be considered as multimodal theranostic agents.

Gd2O3, SiO2-Gd2O3 and SiO2-MnO2 nanoparticles as potential MRI contrast agents