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The main goal of learning science today is the realization of learners who are literate in science. Unfortunately, Indonesian scientific literacy skill is still low based on the assessment of OECD for three evaluation periods. Therefore this study aims to produce an electronic-based learning system in learning science using LMS Chamilo which is intended to enhance students’ scientific literacy skills. This study is research and development (R &amp; D) using the ADDIE model. Research findings indicated that (1) the Chamilo-based e-learning was feasible to implement in biology teaching based on experts judgment with a total score of 3.83 (very good) from environmental material expert and 3.22 (good) from learning media expert; (2) the Chamilo-based e-learning was accepted very well by users with a total score of 3.78 (very good) from biology teachers and 3.36 (very good) from students; (3) the Chamilo-based e-learning was effective in enhancing students’ scientific literacy skills with n gain score of 0.74 (high criteria). Based on the results, it can be concluded that Chamilo-based e-learning is recommended to implement and to use in the biology learning process.

Developing Chamilo-Based E-Learning in Environmental Change Material to Enhance Students’ Scientific Literacy Skills