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PREFACE The rapid development of information and communication technology (ICT) in recent years has shifted us to digital era. The biggest challenge in our world of education is how to reform education system and integrate modern technology in teaching and learning. The development of science and technology has also supported the acceleration of research in this field, as well as giving influence to researchers to continuously improve themselves. In a highly open global information era, sharing creative ideas and cooperations in the field of biosciences and biological education need to be improved through various fora. International Seminar on Bioscience and Biological Education (ISBBE) facilitates to evoke creative and innovative ideas among educators and researchers in the field of bioscience and biological education. In accordance with the focus of the problem, this international seminar has a theme: “Research and Education Innovation on Bioscience for the 21st Century Challenges.” This seminar brought us to discuss recent development and innovation in biological and bioscience research. Several expert in the field of Bioscience and biological education were invited, including Prof. Dr. Mamoru Yamada (Yamaguchi University, Japan), Prof. David F. Treagust (Curtin University, Australia), Dr. Mahani Mokhtar (University of Technology Malaysia, Johor, Malaysia) and Dr. Kriengkrai Satapornvanit (Kasetsart University, Bangkok, Thailand). We are also invited special keynote speaker Dr. Ir. Paristiyanti Nurwardani, MP, Director of Learning Affair, General Directorate of Learning and Student Affairs, The Ministry of Research, Technology, and Higher Education. On behalf of the committee and the institution, I would like to thanks to the participants who had been participated in this seminar. I realy hope that we are going to meet again at the next ISBBE event. Thank you. Yogyakarta, Indonesia, October 2018 ISBBE Chairman Dr. Suyitno Aloysius

The International Seminar on Bioscience and Biogical Education