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Learning difficulties of students in understanding human physiology concepts are caused by the abstract objects because the physiological process occurs inside the human body. The condition causes the student learning outcomes become low. In order to overcome the problem, Quipper School, as an online-based learning media, is develop as a medium. It has various interesting features that facilitate students learning meaningfully and support student learning. This research aims to improve students’ conceptual understanding of biology through Quipper School. This research was conducted at SMA Negeri 2 Ngaglik and SMA Negeri 1 Prambanan in 11 th  grade, using quasi-experiment method, pretest-post-test nonequivalent control group design. Data were collected by using test instruments and analyzed by using normalized gain score and different test with Mann-Whitney U Test. The normalized gain score results showed that both the control and experimental classes increased in the conceptual understanding with medium category, namely of 0.38 and 0.62, respectively. The different tests results indicated that there was a very significant difference between increasing the understanding of science concept in two sample classes, with a significance value of 0.000. Thus, it could be concluded that the use of Quipper School was effectively in improving students’ understanding of scientific concepts.

Improving Students’ Conceptual Understanding of Biology through Quipper School