Open AccessIntegration of pluripotency pathways regulates stem cell maintenance in the Arabidopsis shoot meristem
Author(s) -
Ying Su,
Chao Zhou,
Ying Ju Li,
Yu Yang,
Li Tang,
Wen Jie Zhang,
Wang Jinsong Yao,
Rongfeng Huang,
Thomas Laux,
Xian Sheng Zhang
Publication year - 2020
Publication title -
proceedings of the national academy of sciences of the united states of america
Language(s) - English
Resource type - Journals
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.2015248117
Subject(s) - meristem , arabidopsis , biology , microbiology and biotechnology , induced pluripotent stem cell , shoot , stem cell , cell division , botany , embryonic stem cell , cell , genetics , gene , mutant
Significance Pluripotent stem cells are critical in both animal and plant development. Unlike higher animals, plants have unique postembryonic development, which continuously produce organs depending on shoot and root meristems. In the shoot meristem, division of the stem cells in the outermost layers provides the cells for all shoot structures. How those meristem cells are tightly controlled attracted intense studies. Genetic and molecular analyses inArabidopsis have identified the key transcription factors WUSCHEL (WUS) and SHOOTMERISTEMLESS (STM) as the major regulators of pluripotency in the shoot meristem. Here, the results provide solid evidence showing how those two pluripotency factors WUS and STM coordinate to control shoot meristem cells strictly in plants.