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Primary carcinoid tumor in a polycystic kidney
Author(s) -
Shibata Rie,
Okita Hajime,
Shimoda Masayuki,
Asakura Hirotaka,
Murai Masaru,
Sakamoto Michiie,
Hata Junichi
Publication year - 2003
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.2003.01469.x
Subject(s) - chromogranin a , pathology , synaptophysin , nephrectomy , kidney , enolase , medicine , polycystic kidney disease , immunohistochemistry
A case of a primary carcinoid tumor within a polycystic kidney is reported. A 51‐year‐old woman with autosomal dominant polycystic kidney disease (ADPKD) underwent a bilateral nephrectomy because of an infection in her polycystic kidneys. A tumor (1.5 cm in diameter) was incidentally found close to the hilum of the left kidney. Histologically, the tumor exhibited a predominantly trabecular pattern of cuboidal or columnar cells. Grimelius staining showed numerous silver‐stained neurosecretory granules in most of the tumor cells; the tumor cells were also positive for chromogranin, synaptophysin, prostatic acid phosphatase (PAP) and neuron‐specific enolase (NSE). The tumor was diagnosed as a primary carcinoid tumor of the kidney. Primary renal carcinoid is a very rare neoplasm, and this is the first report of such a lesion arising in a polycystic kidney.