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Viral hepatitis and primates: historical and molecular analysis of human and nonhuman primate hepatitis A, B, and the GB‐related viruses
Author(s) -
Robertson Betty H.
Publication year - 2001
Publication title -
journal of viral hepatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 100
eISSN - 1365-2893
pISSN - 1352-0504
DOI - 10.1046/j.1365-2893.2001.00295.x
Subject(s) - nonhuman primate , virology , biology , primate , hepatitis , virus , viral hepatitis , molecular virology , viral evolution , hepatitis a virus , hepatitis c virus , hepatitis b virus , rna , genetics , evolutionary biology , gene , neuroscience
The hepatitis viruses have long been assumed to be highly host‐specific, with infection of other nonhuman primates occurring due to inoculation with, or exposure to, human viruses. This paradigm has slowly changed over the last 10 years, as mounting data has revealed nonhuman primate equivalents of hepatitis A virus, hepatitis B virus, and the hepatitis C‐related viruses GBV‐C and GBV‐A. This review summarizes the historical and molecular information for each of these groups and highlights the impact of these nonhuman primate hepatitis viruses on our understanding of the evolution of each of these viruses.