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Efficacy of microfiltration in decreasing propofol‐induced pain *
Author(s) -
Davies A. F.,
Vadodaria B.,
Hopwood B.,
Dexter T.,
Conn D.
Publication year - 2002
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1046/j.1365-2044.2002.02602.x
Subject(s) - medicine , propofol , anesthesia , lidocaine , incidence (geometry) , pain control , surgery , physics , optics
Summary In a randomised, double‐blinded, two‐centre trial we evaluated the effect of a microbiological filter (Supor ® , Pall Life Sciences) on propofol injection pain. We studied 336 unpremedicated adult patients, who graded pain experienced during induction of anaesthesia with propofol on a 4‐point verbal rating scale. Use of the microfilter reduced both the incidence and severity of propofol injection pain (p < 0.001). Incidence of severe pain in the filter group was 2.4% compared with 16.6% in the control group. Overall, 33.7% in the filter group experienced pain compared with 62.1% in the control group. A microbiological filter may provide a non‐pharmacological alternative to a lidocaine/propofol mixture for reducing injection pain. It would also reduce the risk of any glass and bacterial contamination.