Open AccessTumour antigen-induced T cell exhaustion — the archenemy of immune-hot malignancies
Author(s) -
Miguel Lopez de Rodas,
Kurt A. Schalper
Publication year - 2021
Publication title -
nature reviews. clinical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.214
H-Index - 155
eISSN - 1759-4782
pISSN - 1759-4774
DOI - 10.1038/s41571-021-00562-5
Subject(s) - antigen , medicine , immune system , cd8 , t cell , phenotype , immunology , effector , cancer research , cell , lung cancer , cytotoxic t cell , tumor microenvironment , immunotherapy , biology , pathology , in vitro , biochemistry , genetics , gene