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Remodelling without a power stroke
Author(s) -
Dutta Arnob,
Workman Jerry L
Publication year - 2013
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2013.166
Subject(s) - nucleosome , chromatin , dna , microbiology and biotechnology , histone , power (physics) , biology , chemistry , genetics , physics , quantum mechanics
Although chromatin remodellers are thought to exert power strokes to move nucleosomes along DNA, two studies in this issue show that a power stroke is not required for efficient remodelling, indicating that the DNA binding domain primarily tethers remodellers to nucleosomes.