Open AccessInteraction of a Phospholipid and a Coagulating Protein: Potential Candidate for Bioelectronic Applications
Author(s) -
Ripa Paul,
Hritinava Banik,
Meshal Alzaid,
D. Bhattacharjee,
Syed Arshad Hussain
Publication year - 2022
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.1c07395
Subject(s) - phospholipid , chemistry , nanotechnology , materials science , biochemistry , membrane
In the present communication, we have investigated the interaction between a biomembrane component 1,2-dioleoyl- sn -glycero-3-phosphocholine (DOPC) and a coagulating protein protamine sulfate (PS) using the Langmuir-Blodgett (LB) technique. The π- A isotherm, π- t characteristics, and analysis of isotherm curves suggested that PS strongly interacted with DOPC, affecting the fluidity of the DOPC layer. Electrical characterization indicates that PS as well as the PS-DOPC film showed resistive switching behavior suitable for Write Once Read Many (WORM) memory application. Trap-controlled space charge-limited conduction (SCLC) was the key mechanism behind such observed switching. The presence of DOPC affected the SCLC process, leading to lowering of threshold voltage ( V Th ), which is advantageous in terms of lower power consumption.