Open AccessDiethylaminosulfur Trifluoride: A Novel, Low-Cost, Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines
Author(s) -
Hongmei Jiang,
Haicheng Shen,
Sha Zhu,
Binbin Wang,
Yujie Yang,
Zhibin g,
Min Yi,
Shiyun Tang
Publication year - 2021
Publication title -
acs omega
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 40
ISSN - 2470-1343
DOI - 10.1021/acsomega.1c03291
Subject(s) - reagent , chemistry , nucleophile , combinatorial chemistry , organic chemistry , catalysis
We report a novel, inexpensive double thiolation reagent that sulfurizes a broad range of imidazo[1,2-α]pyridines under mild conditions. Importantly, diethylaminosulfur trifluoride, as a common nucleophilic fluorinating reagent, was utilized as a novel thiolation reagent.