Open AccessInborn Errors of Immunity: how to diagnose them?
Author(s) -
Anete Sevciovic Grumach,
Ekaterini Goudouris
Publication year - 2021
Publication title -
jornal de pediatria
Language(s) - English
Resource type - Journals
eISSN - 1678-4782
pISSN - 0021-7557
DOI - 10.1016/j.jped.2020.11.007
Subject(s) - medicine , primary immunodeficiency , immunity , immunology , immune dysregulation , immunodeficiency , immune system , autoimmunity , medical diagnosis , pediatrics , intensive care medicine , pathology
Inborn Errors of Immunity are characterized by infectious conditions and manifestations of immune dysregulation. The diversity of clinical phenotypes can make it difficult to direct the laboratory investigation. This article aims to update the investigation of immunological competence in the context of primary defects of the immune system.