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Copper ferrite-copper oxide (CuO-CuFe 2 O 4 ) nanoparticles as a semiconductor composite with p-n junction were synthesized by co-precipitation reaction. Then, a novel CuO-CuFe 2 O 4 carbon paste modified electrode was fabricated which displays an effectual electrocatalytic response to the oxidation of acetaminophen (AC) and codeine (CO). A linear range of 0.01-1.5 μmol L -1 and 0.06-10.0 μmol L -1 with the detection limits of 0.007 μmol L -1 and 0.01 μmol L -1 were achieved for AC and CO, respectively. The practical usage of the proposed sensor revealed reasonable results for quantification of AC and CO in biological fluids.

journal of food and drug analysis

Ultra-sensitive electrochemical sensing of acetaminophen and codeine in biological fluids using CuO/CuFe 2 O 4 nanoparticles as a novel electrocatalyst