Premium
P2‐458: LOWER BASELINE MEMORY PERFORMANCE IS ASSOCIATED WITH INCREASES IN WORRIES ABOUT COGNITIVE PERFORMANCE IN APOE E4 CARRIERS
Author(s) -
Pagen Linda H.G.,
Verhey Frans R.J.,
Boxtel Martin P.J.,
Poser Benedikt A.,
Goebel Rainer,
Jacobs Heidi IL.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2865
Subject(s) - cognition , effects of sleep deprivation on cognitive performance , psychology , episodic memory , mood , cognitive decline , neuropsychology , cognitive test , clinical psychology , medicine , dementia , psychiatry , disease
95% level. Results: Distribution of age, years of education, illiteracy, and catchment area (urban/rural) showed differences among groups. Equally all the cognitive measures, had differences among the three groups. When considering other health problems known as risk factors for cognitive impairment, only depressive symptoms, diabetes and neuropsychiatric symptoms showed differences among the studied groups. ForMCI, participants with saving scores of 80% had an RR of 2.24 (1.37-3.36) (table 1). For dementia, the RR for the delay recall score was 0.79 (0.71-0.87). Those who had savings 80% have 45% more risk for developing dementia in a 3year follow-up (table 2). Conclusions: Impairment in the performance of a verbal learning test, specifically delay recall and savings showed to be risk factors for incident MCI or dementia, even three years before the diagnosis, independently of other risk factors.