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P1‐405: VISUAL ASSESSMENT OF β‐AMYLOID PET SCAN IS IMPROVED BY CAPAIBL
Author(s) -
Dore Vincent,
Bourgeat Pierrick,
Cummins Tia L.,
Raniga Parnesh,
Williams Scott,
Amadoru Sanka,
MacLean Catriona,
Hinton Fairlie,
Shepherd Claire,
Halliday Glenda M.,
Leyton Cristian E.,
Hodges John R.,
Ames David,
Martins Ralph N.,
Masters Colin L.,
Fripp Jurgen,
Salvado Olivier,
Villemagne Victor L.,
Rowe Christopher
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.414
Subject(s) - medicine , nuclear medicine , medical diagnosis , radiology
memory performance in NC, while the SN group maintained highlevel memory performance regardless of the level of glucose metabolism. Conclusions: Preserved whole cortex glucose metabolism, as well as resistance to amyloidosis and glucose hypometabolism in the right isthmus cingulate cortex, contributes to the Supernormal phenomenon. These findings may be informative for the development of early screening biomarkers and therapeutic targets for modification of cognitive trajectories in the face of cognitive aging-associated pathophysiology.