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IC‐P‐012: CONFOCAL ANALYSIS OF FLUORESCENT SIGNAL DERIVED FROM CN‐FLUTEMETAMOL LABELED DIFFUSE AND NEURITIC PLAQUES IN ALZHEIMER'S DISEASE
Author(s) -
Ikonomovic Milos D.,
Buckley Chris J.,
Abrahamson Eric E.,
Mathis Chester,
Klunk William E.,
Farrar Gill
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.2076
Subject(s) - senile plaques , chemistry , pathology , amyloid (mycology) , confocal , alzheimer's disease , fluorescence , nuclear medicine , medicine , optics , physics , disease
average Visit-1 PiB DVRs. Dispersed-1: estimated intermediate propagation. Dispersed-2: estimated full propagation similar to Visit-2. Visit-2: actual average Visit-2 PiB DVRs. Regions (spheres) with PiB DVRs which (1) increase from Visit-1 to Visit-2 and (2) increase via propagation are shown. PiB DVR values are proportional to size and follow the colormap. Only the edges (gray lines) connected to these regions are shown. Red dotted circles: Dispersed-2 has highly accurate propagations compared to actual Visit-2. Poster Presentations: Saturday, July 21, 2018 P21