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[P4–556]: EVALUATING THE ASSOCIATION BETWEEN CENTRAL NERVOUS SYSTEM (CNS)‐ACTIVE MEDICATION USE AND FALL‐RELATED INJURIES IN OLDER ADULTS WITH DEMENTIA
Author(s) -
Hart Laura A.,
Marcum Zachary,
Gray Shelly L.,
Walker Rod L.,
Crane Paul K.,
Larson Eric B.
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.07.719
Subject(s) - medicine , dementia , hazard ratio , poison control , injury prevention , population , proportional hazards model , confidence interval , emergency medicine , physical therapy , disease , environmental health
Background: Substantial studies have reported the prevalence and affecting factors of SCD and complainants screening scale has also been used for probing. However, little is known about SCD due to AD in the the eastern countries, especially in China where subjective cognitive complainant screening scale has not yet been applied. Methods:Stratified cluster random sampling was conducted, and 2688 residents of 60-80 years completed the questionnaire 1 and 814 residents were eventually included for clinical and neuropsychological evaluations. Two standards were used to make the diagnosis of MCI and SCD, and a preliminary screening rate comparison was carried further. Finally, we assessed the risk factors of SCD using multiple logistic regression and correlation between SCD Q and Auditory Verbal Learning Test Long Delay Recall (AVLT LR) . Results: (1) Standard 1(ADNI 2): the prevalence of SCD was 18.8% .(2) Standard 2 (Jak/Bondi) : the prevalence of SCD was 14.4%. (3) Cross-tabulation analysis showed that: standard 1 has a relatively higher‘false’ positive rate, whereas standard 2 has higher‘false’ negative rate. (4) Analysis showed that : aging, low education, less close friends and daily drinking were independent risk factors for SCD progressing to MCI. (5) Total points of SCD Q was negatively correlated to the number of AVLT LR. Conclusions:The prevalence of SCD is higher in Shunyi district of China, and many factors leading to SCD progressing. Brief SCD-Q can be used as a reference.