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[P4–508]: DETECTION OF TAU TANGLES IN THE RETINA
Author(s) -
Kayabasi Umur A.,
Rispoli Marco
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.07.670
Subject(s) - retinal , retina , fundus (uterus) , pathology , autofluorescence , ophthalmology , medicine , neuroscience , biology , optics , physics , fluorescence
a definitive reference model describing regional effects of AD pathology on the hippocampus. Histological studies (e.g. Rossler et al, Acta Neuropathol, 2002; Simic et al., JOCN, 1997) provide limited reference information due to their 2D nature, use of a measure like cell count rather than volume or thickness, and inconsistency between studies. We therefore built a 3D probabilistic atlas of the hippocampus combining post-mortem MRI and histology