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[IC‐P‐177]: FIRST EVALUATION OF THE NEUROFIBRILLARY TANGLES RADIOLIGAND [ 18 F]MK‐6240 IN ALZHEIMER's DISEASE PATIENTS
Author(s) -
Bennacef Idriss,
Lohith Talakad,
Declercq Ruben,
Tom Reynders,
TelanChoing Florestina,
Celen Sofie,
Serdons Kim,
Bormans Guy,
Vandenbulcke Mathieu,
Hoon Jan,
Koole Michel,
Laere Koen,
Vandenberghe Rik,
Sur Cyrille,
Struyk Arie
Publication year - 2017
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2017.06.2552
Subject(s) - radioligand , washout , nuclear medicine , alzheimer's disease , dementia , cortex (anatomy) , chemistry , neuroscience , pathology , medicine , disease , psychology , receptor
Gender (Male/Female) 17/23 Age (years) 62.9 6 8.4 Education (years) 17.5 6 3 Amyloid PET (PIB) Pos / Neg 40/0 MMSE (/30) 22.2 6 5.8 CDR Sum of Boxes (18) 3.9 6 2.3 Episodic Memory (W-score) -2.7 6 1.5 Semantic Memory (W-score) -1.9 6 1.7 Language (W-score) -1.6 6 1.8 Executive functions (W-score) -2.2 6 1.1 Visuospatial functions (W-score) -3 6 3.9 Clinical syndrome 5 MCI and 35 AD (81vPPA 12 PCA) Interval MRI-Neuropsychological exam (days) 27 6 67