P4‐058: Randomized evaluation of mmse and npi in patients using rivastigmine in Alzheimer's disease

primary site of pathology. Genetic testing for known mutations of hereditary leukodystrophy with axonal spheroids was negative. Conclusions:This case describes a new pathologic correlate of Primary Progressive Aphasia, and further shows that the common denominator of diseases causing this syndrome is the asymmetric predilection for the language-dominant hemisphere rather than the cellular nature of the pathology. The patient-specific factors that determine the selective vulnerability of the language-dominant hemisphere in Primary Progressive Aphasia remain to be identified.