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P1‐048: Glucose metabolism in progressive non‐fluent aphasia patients with versus without parkinsonism
Author(s) -
Roh Jee Hoon,
Kim Eun-Joo,
Suh Mee Kyung,
Seo Seo Sang Won,
Na Duk L.
Publication year - 2010
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2010.05.595
Subject(s) - parkinsonism , progressive supranuclear palsy , medicine , aphasia , corticobasal degeneration , pathology , psychiatry , disease
Conclusions: FUS protein accumulation is characteristic in a group of FTLDs with ubiquitin-positive pathology. The clinical features are heterogeneous although the most common association is with bvFTD. Clinical and pathological evidence of MND may be found in cases previously diagnosed as NIFID. FUS-positive inclusions in both cerebral cortex and motor neurons in NIFID and aFTLD-U extend the spectrum of diseases with frontotemporal degeneration and involvement of the motor system.