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IC‐P‐020: 3‐D mapping of episodic memory and executive function in late‐onset depression
Author(s) -
Wang Huali,
Zhang Na,
Zhang MeiYan,
Liao Jing,
Chang Daniel,
Yuan Huishu,
Su MinYing,
Yu Xin
Publication year - 2009
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2009.05.040
Subject(s) - psychology , verbal fluency test , audiology , dementia , trail making test , episodic memory , fluency , recall , voxel , depression (economics) , neuropsychology , executive functions , cognition , medicine , psychiatry , cognitive psychology , mathematics education , disease , macroeconomics , economics , radiology
frontal gyrus, superior parietal lobule, left paracentral lobule, sub-gyral and right thalamus, superior temporal gyrus, middle temporal gyrus (PFWE-cor < 0.01, Figure 1). As for the comparison between aMCI and NC groups, there were no significant suprathreshold clusters at the significance level of Puncorrected < 0.005. Conclusions: AD is characterized with significant regional atrophy in temporal, frontal and parietal lobes, and aMCI presents minor atrophy in cingulate gyrus. It is suggested cingulate gyrus may be one of the earliest affected region in the development of Alzheimer’s disease.