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P4‐075: Mild cognitive impairment and dementia in a Brazilian elderly cohort
Author(s) -
Godinho Claudia C.,
Camozzato Ana Luiza,
Piazensky Isabel,
Chaves Marcia Lorena
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2008.05.2140
Subject(s) - dementia , cohort , medicine , incidence (geometry) , epidemiology , gerontology , cohort study , memory clinic , depression (economics) , cognitive impairment , cognition , disease , clinical dementia rating , cognitive decline , pediatrics , psychiatry , physics , optics , economics , macroeconomics
glucose homeostasis (IPGTT) is observed but this happens only at early stages of the disease when only intraneuronal AB is reported in these animals. Conclusions: These results reinforce the probable contribution of intraneuronal occurrence of AB in the modification of neurophysiological homeostasis. Further studies should be carried out to elucidate the disruption of glucose homeostasis at the appearance of intraneuronal AB and how this relates to the progression of the disease.