Open AccessA systematic review and meta-analysis of antibiotic prophylaxis in skin graft surgery: A protocol
Author(s) -
Mimi R. Borrelli,
Vikram Sinha,
Madeleine L. Landin,
Maria Chicco,
Kezia Echlin,
Riaz Agha,
Alastair Ross
Publication year - 2019
Publication title -
international journal of surgery protocols
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.291
H-Index - 4
ISSN - 2468-3574
DOI - 10.1016/j.isjp.2019.02.001
Subject(s) - medicine , cochrane library , medline , systematic review , cinahl , protocol (science) , meta analysis , randomized controlled trial , antibiotic prophylaxis , scopus , database , adverse effect , data extraction , clinical trial , surgery , intensive care medicine , antibiotics , alternative medicine , pathology , psychological intervention , microbiology and biotechnology , psychiatry , political science , computer science , law , biology
There is little evidence-based guidance on the use of prophylactic antibiotics in skin surgery; whilst antibiotics may protect against surgical site infections (SSI), they have associated side effects, increase the risk of adverse events, and can propagate antibiotic resistance. We present a protocol for a systematic review to establish whether the benefit of prophylactic antibiotics overrides the risk, for patients undergoing autograft surgery.