Open AccessImmunohistochemical findings of the granulomatous reaction associated with tuberculosis
Author(s) -
Shirin Karimi,
Masoud Shamaei,
Mihan Pourabdollah,
Makan Sadr,
Mehrdad Karbasi,
Arda Kiani,
Moslem Bahadori
Publication year - 2016
Publication title -
international journal of mycobacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 20
eISSN - 2212-554X
pISSN - 2212-5531
DOI - 10.1016/j.ijmyco.2016.11.001
Subject(s) - staining , pathology , immunohistochemistry , medicine , granuloma , h&e stain , epithelioid cell , biopsy , mycobacterium tuberculosis , tuberculosis , periodic acid–schiff stain , pathological , ziehl–neelsen stain , lymph node , anatomical pathology , sputum , acid fast
The histological diagnosis of Mycobacterium tuberculosis (MTB) has long been a diagnostic challenge in the anatomical pathology field despite availability of different laboratory methods. Immunohistochemistry (IHC) could not only confirm granulomatous tissue involvement but also demonstrate MTB antigen immunolocalization. This study tries to clarify the details of IHC staining for MTB with pAbBCG.
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