Open AccessMeeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease
Author(s) -
Dougherty Ryan J.,
Ellingson Laura D.,
Schultz Stephanie A.,
Boots Elizabeth A.,
Meyer Jacob D.,
Lindheimer Jacob B.,
Van Riper Stephanie,
Stegner Aaron J.,
Edwards Dorothy F.,
Oh Jennifer M.,
Koscik Rebecca L.,
Dowling Maritza N.,
Gallagher Catherine L.,
Carlsson Cynthia M.,
Rowley Howard A.,
Bendlin Barbara B.,
Asthana Sanjay,
Hermann Bruce P.,
Sager Mark A.,
Johnson Sterling C.,
Okonkwo Ozioma C.,
Cook Dane B.
Publication year - 2016
Publication title -
alzheimer's and dementia: diagnosis, assessment and disease monitoring
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.497
H-Index - 37
ISSN - 2352-8729
DOI - 10.1016/j.dadm.2016.03.005
Subject(s) - atrophy , temporal lobe , medicine , magnetic resonance imaging , physical activity , disease , gerontology , physical therapy , physical medicine and rehabilitation , psychology , psychiatry , radiology , epilepsy
Physical activity (PA) is associated with brain health in older adults. However, it is unknown whether the current physical activity recommendations (PAR) impart substantive benefit. The objective of this study was to compare temporal lobe volumes between older adults who met PAR and those who did not. Methods Ninety‐one enrollees from the Wisconsin Registry for Alzheimer's Prevention wore an accelerometer for seven consecutive days to quantify their PA behaviors and underwent a T‐1 anatomic magnetic resonance imaging scan. Participants were categorized as either having met PAR or not based on the US Department of Health and Human Services recommendations of 150 minutes of moderate‐to‐vigorous physical activity per week. Results Participants who met PAR possessed significantly greater inferior (η 2 P = .050) and anterior (η 2 P = .055) temporal lobe volumes compared with those who did not ( P < .05). Discussion Individuals at‐risk for AD experience accelerated rates of brain atrophy. These results suggest that regular engagement in PA at or above PAR could attenuate this decline.