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Systematization of clinical management for recurrent aborters by combined immunological testing
Author(s) -
Hasegawa I.,
Takakuwa K.,
Kanazawa K.,
Takeuchi S.
Publication year - 1991
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/0020-7292(91)90293-e
Subject(s) - medicine , case fatality rate , immunology , mixed lymphocyte reaction , antibody , lymphocyte , gynecology , epidemiology , immune system , t cell
The natural outcomes of successive new pregnancies of 66 recurrent aborters were analysed in relation to their immunological profiles. The data demonstrated that the presence of anti‐phospholipid antibodies (success rate 6.7%), positive anti‐paternal cytotoxicity (8.7%) and a negative mixed lymphocyte reaction (MLR)‐blocking effect (33.3%) in the patients' sera were factors associated with a poor prognosis. By the combined evaluation of these testings, a rational scheme of clinical management for recurrent aborters was established.