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The nitrogenase MoFe protein
Author(s) -
Gerloff Dietlind L.,
Jenny Thomas F.,
Knecht Lukas J.,
Gonnet Gaston H.,
Benner Steven A.
Publication year - 1993
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(93)80004-e
Subject(s) - nitrogenase , protein superfamily , threading (protein sequence) , protein structure , chemistry , protein structure prediction , protein tertiary structure , biochemistry , biology , crystallography , genetics , gene , nitrogen fixation , bacteria
Surface residues, interior residues, and parsing residues, together with a secondary structure derived from these, are predicted for the MoFe nitrogenase protein in advance of a crystal structure of the protein, scheduled shortly to appear in Nature . By publishing this prediction, we test our method for predicting the conformation of proteins from patterns in the divergent evolution of homologous protein sequences in a way that places the method ‘at risk’.