Open AccessStudy of Spectrum of Chromosomal Rearrangements in Recurrent Pregnancy Loss
Author(s) -
Reema Kumar Bhatt,
Monika Agarwal
Publication year - 2020
Publication title -
journal of obstetrics and gynecology of india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 17
eISSN - 0971-9202
pISSN - 0975-6434
DOI - 10.1007/s13224-020-01305-9
Subject(s) - medicine , pregnancy , chromosomal translocation , obstetrics , gestation , population , products of conception , gynecology , cohort , first trimester , second trimester , pediatrics , genetics , biology , environmental health , gene
Recurrent pregnancy losses (RPLs) are seen in up to 15-20% of all clinically recognized pregnancies, 1-2% of women in general population. Repeated losses are seen in 5-10% of women. The prevalence of chromosomal rearrangements is 6.65% in couples with repeated pregnancy losses. Two to 4% of RPL are associated with parental balanced reciprocal and Robertsonian translocations.