Open AccessIrisin as a Novel Marker for Insulin Resistance in Iraqi Women with Polycystic Ovary Syndrome Before and After Metformin Therapy
Author(s) -
Fatin Shallal Farhan,
Shatha Sami Hussein
Publication year - 2018
Publication title -
journal of obstetrics and gynecology of india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 17
eISSN - 0971-9202
pISSN - 0975-6434
DOI - 10.1007/s13224-018-1176-7
Subject(s) - medicine , polycystic ovary , metformin , hyperinsulinemia , insulin resistance , myokine , anovulation , endocrinology , insulin , outpatient clinic , hyperinsulinism , infertility , gynecology , pregnancy , biology , skeletal muscle , genetics
Polycystic ovarian syndrome affects 5-10% of women; it represents the most common cause of hyperinsulinemia with anovulation. Many biomarkers are used to assess insulin resistance. Irisin is a newly discovered myokine associated with insulin resistance and other metabolic syndromes.