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Sickle cell disease (SCD) is a genetic disorder with an estimated 5200 live births each year indicating towards a major public health issue in India. Although SCD has been described in India in numerous ethnic groups, it is most prevalent in tribal community. Prevalence of sickle cell gene is 5 to 34% in tribal communities, who have a high prevalence of socioeconomic disadvantage and are frequently medically underserved. The objective of the present study is to explore the knowledge, awareness, and attitude of premarital genetic counseling and screening for sickle cell hemoglobin among individuals of Koraput district. A cross-sectional study design was employed and a total of 152 individuals were recruited using multistage sampling technique, including 43 individuals with sickle cell hemoglobinopathy. Data was collected using a pre-tested, self-administered questionnaire and analyzed using SPSS-20. Though people are aware of SCD and SCT, majority believe that sickle cell carriers transmit the disease and they do not know that marriage between sickle cell carriers need to be avoided.

Knowledge, awareness, and attitude of premarital screening with special focus on sickle cell disease: a study from Odisha