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The Complex and Important Cellular and Metabolic Functions of Saturated Fatty Acids
Author(s) -
Legrand Philippe,
Rioux Vincent
Publication year - 2010
Publication title -
lipids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 120
eISSN - 1558-9307
pISSN - 0024-4201
DOI - 10.1007/s11745-010-3444-x
Subject(s) - lipogenesis , polyunsaturated fatty acid , biochemistry , myristoylation , clinical chemistry , lipidology , transcription factor , bioavailability , saturated fatty acid , chemistry , metabolism , fatty acid , biology , gene , bioinformatics , phosphorylation
This review summarizes recent findings on the metabolism and biological functions of saturated fatty acids (SFA). Some of these findings show that SFA may have important and specific roles in the cells. Elucidated biochemical mechanisms like protein acylation (N‐myristoylation, S‐palmitoylation) and regulation of gene transcription are presented. In terms of physiology, SFA are involved for instance in lipogenesis, fat deposition, polyunsaturated fatty acids bioavailability and apoptosis. The variety of their functions demonstrates that SFA should no longer be considered as a single group.