Open AccessPeripheral-to-central ratio of Guttae: validity and reliability of an objective method to characterize severity of Fuchs endothelial corneal dystrophy
Author(s) -
Rohan Bajaj,
Michael J. Fliotsos,
Tejus Pradeep,
Allen O. Eghrari
Publication year - 2020
Publication title -
graefe's archive for clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.196
H-Index - 101
eISSN - 1435-702X
pISSN - 0721-832X
DOI - 10.1007/s00417-020-04985-1
Subject(s) - peripheral , ophthalmology , medicine , eye disease , receiver operating characteristic , surgery
Common methods of measuring severity of Fuchs endothelial corneal dystrophy (FECD) are limited in objectivity, reliability, or start with a variable baseline that prevents distinguishing healthy from affected eyes. The aim of this study was to describe a method of grading FECD that overcomes these limitations.