Premium
COVID ‐19 during pregnancy: non‐reassuring fetal heart rate, placental pathology and coagulopathy
Author(s) -
Mongula J. E.,
Frenken M. W. E.,
van Lijnschoten G.,
Arents N. L. A.,
de WitZuurendonk L. D.,
Schimmelde Kok A. P. A.,
van Runnard Heimel P. J.,
Porath M. M.,
Goossens S. M. T. A.
Publication year - 2020
Publication title -
ultrasound in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.202
H-Index - 141
eISSN - 1469-0705
pISSN - 0960-7692
DOI - 10.1002/uog.22189
Subject(s) - medicine , coagulopathy , obstetrics , placenta , obstetrics and gynaecology , fetus , pregnancy , gynecology , fibrin , surgery , immunology , biology , genetics
We report a case of a pregnant woman with COVID‐19 who developed coagulopathy in the absence of severe clinical symptoms. A polymerase chain reaction test of a vaginal swab was positive for SARS‐CoV‐2 RNA, suggesting a possibility of perinatal transmission. Cesarean delivery was performed because of a non‐reassuring fetal heart rate; the placenta showed increased perivillous fibrin deposition and intervillositis. Moreover, placental infection with SARS‐CoV‐2 was demonstrated by placental immunostaining. The findings suggest a possible relationship between placental fibrin deposition and chronic and acute intervillositis, non‐reassuring fetal heart rate and coagulopathy in pregnant women with COVID‐19. © 2020 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.