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A Total Synthesis Trilogy: Calicheamicin γ 1 I , Taxol ® , and Brevetoxin A
Author(s) -
Nicolaou K. C.,
Hale Christopher R. H.,
Nilewski Christian
Publication year - 2012
Publication title -
the chemical record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.61
H-Index - 78
eISSN - 1528-0691
pISSN - 1527-8999
DOI - 10.1002/tcr.201200005
Subject(s) - calicheamicin , physics , radiochemistry , chemistry , nuclear physics , myeloid leukemia , immunology , biology
Abstract Detailed behind‐the‐scenes accounts of the total syntheses of calicheamicin γ 1 I , Taxol ® , and brevetoxin A are discussed with particular emphasis placed on strategies and tactics employed in these campaigns. DOI 10.1002/tcr.201200005