Open AccessMaturation hierarchy of leukemic stem cells
Author(s) -
Löwenberg Bob,
Terpstra Wim
Publication year - 1998
Publication title -
stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.159
H-Index - 229
eISSN - 1549-4918
pISSN - 1066-5099
DOI - 10.1002/stem.5530160810
Subject(s) - biology , progenitor cell , stem cell , myeloid leukemia , leukemia , progenitor , cancer research , immunology , microbiology and biotechnology
Here we discuss the characteristics of various progenitor cell assays for human acute myeloid leukemia (AML) with emphasis on the repopulating properties of human AML progenitor cells, their potential relevance for pathophysiological studies, and treatment development in AML.