Open AccessAcute radiation disease and biological dosimetry in 1993
Author(s) -
Vorobiev Andrei I.
Publication year - 1997
Publication title -
stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.159
H-Index - 229
eISSN - 1549-4918
pISSN - 1066-5099
DOI - 10.1002/stem.5530150736
Subject(s) - biodosimetry , ionizing radiation , acute radiation syndrome , biology , population , dosimetry , bone marrow , physiology , nuclear medicine , medicine , stem cell , irradiation , environmental health , immunology , haematopoiesis , genetics , physics , nuclear physics
Abstract Mankind is at risk for accidental exposure to ionizing radiation. The experience in evaluating and treating victims of radiation exposure is briefly reviewed based upon accidents occurring over the past 25 years. Individual cases of acute toxicities to the skin, gastrointestinal tract, liver and bone marrow are presented. Biodosimetry (utilizing chromosome analysis of peripheral blood lymphocytes and bone marrow and electron spin resonance spectrometry of dental enamel) has been utilized in radiation accidents to assess individual dose. Variability in the dose of ionizing radiation received is typical among the population affected by the Chernobyl accident. Whereas the acute radiation syndrome resulting in a high mortality has been well‐documented, little information is available regarding the effects of chronic, low‐level exposure from the Chernobyl accident. Stem Cells 1997; 15(suppl 2): 269‐274