Hollow Structure Improved Anti‐Cancer Immunity of Mesoporous Silica Nanospheres In Vivo | Zendy

Wang Xiupeng | Zendy; Li Xia | Zendy; Ito Atsuo | Zendy; Yoshiyuki Kazuko | Zendy; Sogo Yu | Zendy; Watanabe Yohei | Zendy; Yamazaki Atsushi | Zendy; Ohno Tadao | Zendy; Tsuji Noriko M. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Hollow Structure Improved Anti‐Cancer Immunity of Mesoporous Silica Nanospheres In Vivo

Author(s) -

Wang Xiupeng,

Li Xia,

Ito Atsuo,

Yoshiyuki Kazuko,

Sogo Yu,

Watanabe Yohei,

Yamazaki Atsushi,

Ohno Tadao,

Tsuji Noriko M.

Publication year - 2016

Publication title -

small

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.785

H-Index - 236

eISSN - 1613-6829

pISSN - 1613-6810

DOI - 10.1002/smll.201600677

Subject(s) - in vivo , mesoporous silica , mesoporous material , nanotechnology , immunity , cancer , in vitro , materials science , splenocyte , cancer immunotherapy , chemistry , immunotherapy , biology , immune system , immunology , biochemistry , microbiology and biotechnology , catalysis , genetics

Hollow and non‐hollow mesoporous silica nanospheres are synthesized and used for cancer vaccine adjuvants. The hollow structure of mesoporous silica nanospheres significantly promote cellular uptake of a model cancer antigen by macrophage‐like cells in vitro, improve anti‐cancer immunity, CD4 + and CD8 + T cell populations in splenocytes of mice in vivo.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research