Open AccessCerebral sinovenous thrombosis in pediatric hemolytic uremic syndrome
Author(s) -
Wyatt Kirk D.,
Rodriguez Vilmarie,
Youssef Paul E.,
Eckel Laurence J.,
Warad Deepti M.
Publication year - 2020
Publication title -
research and practice in thrombosis and haemostasis
Language(s) - English
Resource type - Journals
ISSN - 2475-0379
DOI - 10.1002/rth2.12329
Subject(s) - medicine , complication , hemodialysis , thrombosis , presentation (obstetrics) , pediatrics , surgery
Hemolytic uremic syndrome (HUS) may result in thrombotic central nervous system complications. We present a child with diarrhea‐associated HUS who developed new‐onset focal seizures secondary to cerebral sinovenous thrombosis (CSVT). Her CSVT was treated with low‐molecular‐weight heparin. The patient’s seizures were controlled with levetiracetam, and her HUS was managed supportively with hemodialysis. Repeat imaging nearly 6 months following presentation and initiation of anticoagulation demonstrated cerebral sinus enlargement and persistent intraluminal webbing. Anticoagulation was discontinued after 6 months, and she did not experience long‐term gross neurologic sequelae. CSVT is a complication of HUS that has not been previously described. In this report, we summarize the thrombotic central nervous system complications of pediatric HUS.