Open AccessMorphologically poor blastocysts could affect the implantation rate of a morphologically good blastocyst during a double‐blastocyst transfer for patients who have experienced repeated implantation failures
Author(s) -
Ohgi Shirei,
Taga Yukino,
Anakubo Hisayo,
Kurata Yuki,
Hatakeyama Shota,
Yanaihara Atsushi
Publication year - 2018
Publication title -
reproductive medicine and biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.005
H-Index - 22
eISSN - 1447-0578
pISSN - 1445-5781
DOI - 10.1002/rmb2.12097
Subject(s) - blastocyst transfer , blastocyst , pregnancy rate , andrology , embryo transfer , gynecology , statistical significance , medicine , cryopreservation , embryo , pregnancy , chemistry , biology , embryogenesis , genetics
Purpose Increasing the number of transferred blastocysts sometimes is selected for patients with repeated implantation failure ( RIF ). To confirm this strategy, the pregnancy rates ( PR s) were compared among the groups who had transferred either a single morphologically good blastocyst ( MGB group), double blastocysts with both a MGB and a morphologically poor blastocyst ( MGB + MPB group), or a double‐ BT with 2 MGB s (two‐ MGB group). Methods This study was performed between April, 2009 and September, 2014, including 634 cycles for 354 patients with RIF . All the patients received cryopreserved blastocysts in either hormone replacement or natural ovulatory cycles. The included MGB s were at more than the Gardner grade 3 BB stage. The PR and implantation rates ( IR s) among the three groups were statistically evaluated by the chi‐square test. Statistical significance was set at P < .01. Results Although the PR s were similar in these three groups, the IR in the MGB + MPB group was significantly lower than that of the MGB group. The rate in the two‐ MGB group also was significantly lower than that of the MGB group. Conclusion A double‐ BT with a MGB and a MPB does not increase the pregnancy rate, compared with a single‐ BT with a MGB among patients with RIF .