Open AccessUterus transplantation: Toward clinical application in Japan
Author(s) -
Suganuma Nobuhiko,
Hayashi Ayako,
Kisu Iori,
Banno Kouji,
Hara Hisako,
Mihara Makoto
Publication year - 2017
Publication title -
reproductive medicine and biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.005
H-Index - 22
eISSN - 1447-0578
pISSN - 1445-5781
DOI - 10.1002/rmb2.12048
Subject(s) - transplantation , medicine , infertility , reproductive medicine , uterus , gynecology , organ transplantation , obstetrics , family medicine , pregnancy , surgery , biology , genetics
Background In recent years, uterus transplantation ( UT x) has been applied as the treatment for patients with uterine factor infertility worldwide. Thus, the clinical application of UT x in Japan should be considered through both the history of UT x technology development in the world and future prospects. Methods Recent information on UT x was collected via a literature survey and the Internet. Results Basic research using various animals has been done mainly since 2000. In 2014, the world's first UT x baby was born in Sweden. In total, 24 UT x procedures have been performed at 10 institutes in nine countries and five births were obtained (as of May, 2017). In Japan, the “Project Team for Uterus Transplantation” initiated UT x experiments in 2008 and the “Japan Society for Uterus Transplantation” was organized in March, 2014. In the rest of the world, the “International Society for Uterus Transplantation” was established in January, 2016. Conclusion Uterus transplantation is still under development as a reproductive medicine tool and organ transplant procedure. A collaborative system that is not limited by facilities and specialties should strive to build an “all‐Japan” team.